Prevalence and genotypic characteristics of Panton-Valentine Leukocidin-producing Staphylococcus aureus isolates obtained in Jos, North Central Nigeria

Panton-Valentine Leukocidin–producing Staphylococcus aureus

To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by <5% of S. aureus strains, the toxin is detected in large percentages of isolates that cause necrotic skin lesions and severe necrotizing pneumonia (2). Although commonly associated with community-acquired methicillin-re...

Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.

We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.

Panton-Valentine Leukocidin Genes in Staphylococcus aureus

To the Editor: The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furuncu...

Panton-Valentine Leukocidin–positive Staphylococcus aureus, Singapore

Trichinella papuae and Trichinella zimbab-wensis induce infection in experimentally infected varans, caimans, pythons and turtles. Trichinellosis: recommendations on methods for the control of Trichinella in domestic and wild animals intended for human consumption. La Rosa G. PCR-derived methods for the identification of Trichinella parasites from animal and human samples. The identification an...

Prevalence of Panton-Valentine leukocidin genes among carriage and invasive Staphylococcus aureus isolates in Malaysia.